The burglaries happened in Belfast and Craigavon.
Police said three men were seen leaving the properties in an SUV.
PSNI Detective Sergeant Stewart said: “Police first received a report at approximately 6.20pm of a burglary in the Gracefield Lodge area of Craigavon.
“It’s understood entry was gained to the house via a rear door which had been smashed.
“A number of rooms had been ransacked inside the property, and enquiries are ongoing to determine if anything, was stolen.
“A short time later at around 7.45pm we received another report of a burglary at a house in the Shore Road area of north Belfast.
“Entry was gained through a front door and areas of the property were also ransacked. We’re also continuing to investigate if anything was taken.
“Three masked men were observed leaving this property and are all described as being of slim build, and wearing dark-coloured clothing.
“They left the scene in a dark-coloured SUV type vehicle – which we believe could be potentially connected to the earlier burglary in Craigavon.
“Both of these properties were vacant when the burglaries occurred, and we would encourage homeowners to make security a central part of the daily routine. Please do not keep large amounts of money at home or carry it on your person.
“Thieves have been known to employ a number of tactics to establish the routines and habits of business owners, such as following them to and from their home, place of business, wholesalers or suppliers, and even determining the frequency of trips to the bank to determine if cash deposits from the business are being kept in the home.
“Conduct regular security checks of your home and business – are doors and windows secure, is there an alarm or other security system fitted and working? If you don’t have CCTV or a doorbell camera, consider installing one. Invest in a dash-cam.
“Most importantly, if you see anything or anyone suspicious, or have any concerns that your business may be a target, contact police right away.”
Police urged anyone with information to contact the non-emergency 101 number.