The yellow warning is currently in place for 47 hours, from 12pm on Saturday, January 4 until 9am on Monday, January 6.
The warning covers a large part of the UK as temperatures are expected to drop following the windy start to 2025.
The Met Office said that parts of the Midlands, Wales and Northern England are most at risk of disruption, where 5cm or more could accumulate “fairly widely”.
People are being urged to check before they travel, with possible disruption to the roads, public transport and air travel.
The forecaster has also warned there could be a small chance of power cuts and disruption to mobile phone service, as well as a slight chance some rural communities may become cut off.
Yellow warning of snow affecting West Midlands https://t.co/zR1tYcuvXO pic.twitter.com/1SMDln2sy6
— Met Office – West Midlands (@metofficeWMids) January 1, 2025
Dan Holley, a Deputy Chief Forecaster for the Met Office, said: “An Atlantic frontal system is likely to move across parts of central and southern UK through the weekend.
“With milder, moisture-laden air engaging with the cold conditions already in place, this may bring a spell of snow in some areas, before possibly turning back to rain in the south.
“At this stage, there is a fair amount of uncertainty over exactly which areas will see disruptive snow, with parts of Wales, northern England and the Midlands most likely to see some impacts.
“Here we could see 5cm or more in quite a few areas, and perhaps as much as 20-30cm over high ground, including Wales and the Pennines.
“Coupled with strengthening winds this could lead to drifting, making travelling conditions difficult over higher-level routes in particular.
“We’ve currently issued a yellow warning for snow covering a large part of England, Wales and southern Scotland to cater for possible disruption over the weekend, but it’s quite likely this will be refined over the coming days as confidence in the forecast increases. So it’s worth keeping up to date with the latest warnings.”