The homeware company, part of TJX International, which owns TK Maxx, has confirmed the closure date with signs in the window of its Churchill Way West store.
This follows the closure of neighbouring Smyths Toys on Sunday, January 5.
Lidl has submitted plans to fill the vacant units at the retail park with its second supermarket in Salisbury.
Read more: Families ‘gutted’ as closure of Smyths Toys ‘marks very sad day for Salisbury’
The company says it will ‘see customers soon’ elsewhere (Image: Newsquest) A Homesense spokesperson said: “Our store will be closing during the week of February 24.
“We appreciate the support of our loyal customers and associates over the years.
“We look forward to welcoming you to TK Maxx Salisbury in Cross Keys Arcade, where you can continue to find high-quality, top-brand homeware, fashion, gifts, and childrenswear at amazing value.
“You can also shop online at TKMaxx.com or find your nearest store at HomeSense.com or TKMaxx.com.”
Salisbury customers’ closest Homesense stores will be in Southampton (Above Bar Street) and Bournemouth (Castlepoint Shopping Centre).